With Pattinson due to play for Australia in the Champions Trophy, Pujara will come in for four County Championship matches.
Pujara, who averages 51.32 after 48 Tests, will play in two games against Gloucestershire and one each against Glamorgan and Derbyshire -- one of his former teams.
"I'm ready for it. I'm already working on my skills and preparing for competitive cricket," Pujara, 29, said in a press release.
"I love playing county cricket and Trent Bridge is a great venue. I'm really looking forward to my first experience there as a home player."