China’s second gene-edited foetus is 12-14 weeks old: scientist

The second woman carrying a gene-edited foetus in China could now be 12 to 14 weeks into her pregnancy, according to a US physician in close contact with the researcher who claimed to have created the world’s first genetically-modified babies last year. Chinese scientist He Jiankui shocked the scientific community after revealing that he had successfully altered the DNA of twin girls born in November to prevent them from contracting HIV.

State media reported on Monday that a preliminary investigation confirmed that a second woman became pregnant and that she will be put under medical observation, but no other details about her are known. Professor He, who now faces a police investigation, had mentioned the potential second pregnancy at a human genome conference in Hong Kong in late November, but its status was unclear until now.

William Hurlbut, a physician and bioethicist at Stanford university in California who has known He for two years, told AFP it was “too early” at the time for the foetus to appear on an ultrasound. Based on extensive conversations with He, Hurlbut said: “I get the impression the baby was fairly young when the conference happened. It could only be detected chemically, not clinically (at the time). “So it could be no more than four to six weeks old (at the time), so now it could be about 12 to 14 weeks.”

Hurlbut said he met He at a scientific conference co-chaired by Hulburt two years ago. Since then the pair have met at least four times during He’s visits to Stanford. Hurlbut added he was not involved in He’s project in any capacity, and only knows about the second pregnancy from what He has told him.

Wang Haoyi, a Development Biologist at the Chinese Academy of Sciences, told AFP that the experiment’s effects on the health of the twin babies is hard to predict, but that their identities should be protected to give them the best chance of a normal life. “I think we definitely need to take serious measures to protect their privacy,” he said. “We don’t even need to let them know that they are any different from others.”